Analysis of erectile dysfunction drugs and their analogues in counterfeit drugs and herbal medicines by LC-ESI-MS/MS
نویسندگان
چکیده
منابع مشابه
Development and validation of a UHPLC-UV method for the detection and quantification of erectile dysfunction drugs and some of their analogues found in counterfeit medicines
Pharmaceutical counterfeiting is a permanently growing problem. Control laboratories are constantly analysing counterfeit medicines. In industrialised countries, one of the main counterfeited class of medicines are erectile dysfunction drugs. This paper describes the development and validation of a fast method to detect and quantify the three authorised phosphodiesterase type 5 inhibitors and f...
متن کاملAnalogues of erectile dysfunction drugs: an under-recognised threat.
OBJECTIVES To investigate the problem of drug analogue adulteration in male erectile dysfunction health products. DESIGN Survey of over-the-counter male erectile dysfunction health products available in convenience stores and pharmacies in Hong Kong. SETTING Tertiary referral centre for clinical toxicology analysis in Hong Kong. MAIN OUTCOME MEASURES The pattern and extent of adulteration...
متن کاملAnalysis of Counterfeit Drugs
Economical and reliable thin layer chromatography methods for rapid screening of counterfeit drugs are described. The methods, which can be carried out in the field by inspectors with limited expertise, are based on the use of portable kits with standard reference tablets to eliminate weighing. Separations are performed on silica gel layers containing fluorescent indicator, and separated spots ...
متن کاملInteractions Between Chinese Herbal Medicines and Drugs
The popular use of herbal products in the general community raises concerns for potential herb– drug interactions. The risk of herb–drug interactions is increased if the herbal medicines are used concurrently with drugs which have a narrow therapeutic range, or are used in certain groups of patients, such as the elderly or those with impaired liver and renal functions. This short paper reviews ...
متن کاملThe dangers of sexual enhancement supplements and counterfeit drugs to “treat” erectile dysfunction
Counterfeit phosphodiesterase-5 inhibitors (PDE-5i) are an increasing problem. Already in widespread use, the market for PDE-5i is steadily growing as the population ages. Counterfeiters are taking advantage of this growing market by developing illicit and counterfeit PDE-5i products. Many factors are contributing to the rapid growth of the illicit market, such as the low risk of prosecution, p...
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ژورنال
عنوان ژورنال: Analytical Science and Technology
سال: 2016
ISSN: 1225-0163
DOI: 10.5806/ast.2016.29.4.155